Micky van de Ven Double Halts Everton's Run at Brand New Stadium
Micky van de Ven became the initial defender to score twice in a English top-flight match for Spurs since the Belgian defender in March 2013.
At a glance
Micky Van de Ven heads home twice in first half
The home side's Jake O'Brien has goal disallowed after VAR review
Senegalese midfielder nets final goal in 89th minute
The defeat is Everton's first at Hill Dickinson Stadium
Micky van de Ven scored twice as Tottenham prolonged their winning streak on the road in the top division and delivered the Toffees their first defeat at their new home.
The Toffees were undefeated in their five previous fixtures at their new ground at the dockside location, having left Goodison Park behind after 133 years at the end of the previous campaign.
But Tottenham's leader the Dutchman pounced twice from corners in the opening 45 minutes to put their impressive record at risk, and they were failed to turn it around before the midfielder - set up by former Toffees attacker the Brazilian - headed home a third to seal the victory.
The Everton defender believed he had equalized the scores five minutes after Van de Ven's opener, glancing a bullet header past Guglielmo Vicario from an set-piece.
Beto, in the meantime, missed a handful of chances, while Vicario made a series of excellent saves to ensure Tottenham went five matches on the road unbeaten in the English top flight.
But the VAR intervened, instructing Craig Pawson to review the score on the screen and the referee ruled that the winger and the attacker were in offside positions and had impeded with the Spurs keeper.
The win elevates Thomas Frank's side into third place in the division, five points off north London rivals and table-toppers Arsenal.
The Merseyside club stay in 14th position and sit half a dozen points clear of the drop zone.
Spurs breakdown: The defender fulfils role at each end of pitch
After a drab midweek display in the European competition against Monaco, where they mustered a mere two shots on target, Frank opted for the French striker in attack instead of former Toffees player the Brazilian.
The summer signing was failed to make much of an impact before being substituted for the substitute after 60 minutes on the field, but it emerged he wasn't needed in the end.
Centre-back Van de Ven converted into an offensive threat to be feared.
Spurs' first goal came from a cleverly executed set-piece play, with the midfielder directing the ball toward the six-yard box for an free the defender to score.
And the captain - stepping up as skipper in Cristian Romero's unavailability - added his second in added time as he rose above Jordan Pickford to head home.
The Dutchman was equally impressive in defence, partnering effectively with his defensive colleague as the pair dealt superbly with the numerous deliveries thrown their way by Everton.
Toffees breakdown: Everton missing finishing touch
The club's recent stadium had been a happy hunting ground, but it seems the novelty may have faded somewhat and fans headed to the exits after Sarr's final goal for Spurs.
The break in the team's winning streak at home will not be a major worry for David Moyes, but their striker situation will be.
Beto and Thierno Barry - the Toffees' two recognised centre-forwards - had netted only one league goal combined before Sunday's outing.
And they were failed to add to that miserable record on a damp and dreary evening on Merseyside.
The striker's form was epitomized when he opted to bicycle-kick a golden opportunity from near the goal, even with having room and opportunity to readjust for a more conventional shot that would have tested Vicario.
The substitute, too, failed to influence the game after coming on for Beto in the second half.
It wasn't for a shortage of chance. The majority of Everton's offensive moves came through the winger and Ndiaye, who tirelessly whipped threatening crosses into the Spurs penalty area.
Upcoming fixtures for these two sides?
Everton: Moyes' men travel to the Stadium of Light in the Premier League on Monday, 3 November at 8 PM.
Tottenham: The London club travel to St James' Park on Wednesday, 29 October for their next round League Cup tie against Newcastle.